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  • Pigmentary keratitis is a discoloration of the cornea due to chronic inflammation and is most common in brachycephalic breeds. In many cases, complete resolution cannot be achieved, but the condition can be stopped or slowed down if the underlying cause can be identified and treated. Surgery and medications may be used to help address the problem.

  • Pituitary macroadenomas are large tumors of the pituitary gland that are either functional (secrete hormones) or non-functional (do not secrete hormones). The clinical signs depend on the type of macroadenoma, though become severe over time in either case. Diagnosis requires specialized CT or MRI imaging. This handout explains the effects of macroadenomas in cats and the treatment options available.

  • Pituitary macroadenomas are large tumors of the pituitary gland that are either functional (secrete hormones) or non-functional (do not secrete hormones). The most common functional pituitary macroadenoma in the dog secretes the hormone ACTH, causing increased cortisol levels and Cushing’s disease. Non-functional macroadenomas cause clinical signs through compression of nearby structures resulting in vision changes, diabetes insipidus, and neurologic disorders. This handout explains the effects of these tumors on dogs, how they are diagnosed, and the treatment options available.

  • Many birds naturally eat plants as part of their diet. Some birds will chew on and possibly consume plants out of curiosity or during play. Many toxic plants will just make a bird sick if they ingest them, but some can kill them. Fortunately, rather than ingesting plants, most birds shred and play with plants with which they come in contact. This handout catalogues many of the indoor and outdoor plants that are considered to be potentially toxic to birds.

  • Plasma cell tumors develop as a result of dysregulated production of plasma cells and are relatively uncommon in dogs and cats. Some plasma cell tumors are benign and the most common locations for these tumors are the head, feet, lips, mouth, and ears. The treatment of choice for benign plasma cell tumors is surgical removal, with little to no recurrence if completely excised. Conversely, multiple myeloma is a very malignant cancer that is usually treated with chemotherapy.

  • Some cats do not seem to know their strength and do not recognize that they are causing pain to their play partners. Accidental bites and scratches can be painful and cause infection, so it is important to find ways to play safely. With training, you may be able to use a verbal cue to redirect your cat if he becomes overly aroused during play.

  • Pleural effusion is the abnormal accumulation of fluid in the chest cavity. Fluid accumulates in the pleural sac, not the lungs, so the lungs are essentially floating in a chest full of fluid. This fluid occupies space within the chest, so the lungs cannot expand as fully as they should. Treatment and prognosis vary depending on the underlying cause.

  • Pododermatitis is a term used to describe inflammation of the feet or paws. It can be caused by many disorders including infections, allergies, hormonal disorders, immune-mediated diseases, tumors or cancers. Diagnostic testing is discussed. Effective treatment must be directed toward the underlying cause.

  • Polycystic Kidney Disease (PKD) is an inherited condition that causes multiple cysts (fluid pockets) in the kidneys. Persian cats and breeds with Persian bloodlines are most commonly affected. The clinical signs, diagnosis, genetic testing, and treatment options are explained in this handout.

  • Polysulfated glycosaminoglycan is an injectable disease-modifying osteoarthritis drug (DMOAD) used to treat non-infectious and traumatic arthritis in dogs. It is also used off-label in cats and small mammals. If administering this medication at home, follow your veterinarian’s instructions and dispose of the needle and syringe appropriately. Side effects are rare when given according to label recommendations and at prescribed intervals. Do not use this medication in pets with a known hypersensitivity to it, in pets with known or suspected bleeding disorders or immune-mediated arthritis, or in pets with severe kidney or liver disorders.